Products has been launched now.

Overview 

  CBI-HFF, as the first-in-class human feeder cell of fetal origin, is our benchmark product. The cell line used to produce CBI-HFF has been well established and documented through a series of cGMP banking process in Europe, and also has been used to manufacture clinical research product (Taiwan, Japan, and the US) for wound healing purpose. CBI-HFF will be provided in research- and clinical-grade to meet our customers’ varied needs.

   Research grade CBI-HFF is produced in Class 100,000 clean room environment, whereas the clinical-grade product will be produced in the highest quality in compliance with the GMP principle to support therapeutic product development of our customers. In short, we intend to provide our valued customers a seamless and painless experience in the feeder cell systems switches while they advance their cell therapy products from research into clinical stage.

​Features

  • Applicable for culture of human ES/iPS cells

  • Mitomycin-C treated cell and ready to use

  • High quality validation and Lot to lot consistency

  • Free of mycoplasma and mibrobial contamination

  • Seamless switch between CBI’s research/clinical grade and different feeder/non-feeder culture system

Contents & Storage​

  • Cryopreserved human fetal fibroblasts  

  • Store in liquid nitrogen

Capstone Biotek’s Human Fetal Fibroblast, HFFs, are tested comprehensively on human embryonic stem cells and iPS cells to ensure consistent and robust performance.

This products has been launched now.

If you have any interest, please feel free to contact us.

COA
CBI010120
CBI010140
CBI010220
CBI010240
References

  1. Richards M, Fong CY, Chan WK, Wong PC, Bongso A. Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells. Nat Biotechnol. 9, 933-936 (2002).

  2. Hovatta O, Mikkola M, Gertow K, Strömberg AM, Inzunza J, Hreinsson J, Rozell B, Blennow E, Andäng M, Ahrlund-Richter L. A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells. Hum Reprod. 7, 1404-1409 (2003).

  3. Lee JB, Song JM, Lee JE, Park JH, Kim SJ, Kang SM, Kwon JN, Kim MK, Roh SI, Yoon HS. Available human feeder cells for the maintenance of human embryonic stem cells. Reproduction 6, 727-735 (2004)

  4. Takahashi K1, Narita M, Yokura M, Ichisaka T, Yamanaka S. Human induced pluripotent stem cells on autologous feeders. PLoS One 12 (2009).

  5. Aguilar-Gallardo C, Poo M, Gomez E, Galan A, Sanchez E, Marques-Mari A, Ruiz V, Medrano J, Riboldi M, Valbuena D, Simon C. Derivation, characterization, differentiation, and registration of seven human embryonic stem cell lines (VAL-3, -4, -5, -6M, -7, -8, and -9) on human feeder. In Vitro Cell Dev Biol Anim. 46, 317-326 (2010).

  6. Zhang YS, Lu ZY, Yu Y, Li XR, Li WB, Wang YN, Geng Y. Derivation, culture and retinal pigment epithelial differentiation of human embryonic stem cells using human fibroblast feeder cells. J Assist Reprod Genet. 8, 735-744 (2012)

For more information or any inquiries, please feel free to contact us, thank you!
  • Maintain pluripotency of iPS/hESC.

  • Lot to lot consistency

  • Save time and money

  • Ready to use

Address: 4F, No. 24, Ln. 50, Sec. 3, Nangnag Rd., 11510 Taipei, Taiwan

Tel: +886-2-27835508   Fax: +886-2-27835080

Email: service@capstone-biotek.com